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Metabolism Diazepam is N-demethylated by CYP3A4 and 2C19 to the active metabolite N-desmethyldiazepam, and is also hydroxylated by CYP3A4 to your Lively metabolite temazepam.I've had a grandmal seizure and wound up in healthcare facility ,i have discovered diazapam really handy with protecting against any more seizures also i suffer from pms and ge